CSCIED

期刊目次

加入编委

期刊订阅

添加您的邮件地址以接收即将发行期刊数据:

Open Access Article

International Journal of Clinical Research. 2023; 7: (8) ; 22-26 ; DOI: 10.12208/j.ijcr.20230290.

Diagnosis and risk factors analysis of fatty liver in physical examination population in Chibi city
赤壁市体检人群脂肪肝的诊断及其危险因素分析

作者: 潘石翠 *, 唐莉, 陈美惠, 高彬

湖北省赤壁市疾病预防控制中心 湖北赤壁

*通讯作者: 潘石翠,单位:湖北省赤壁市疾病预防控制中心 湖北赤壁;

发布时间: 2023-08-20 总浏览量: 212

摘要

目的 掌握赤壁市体检人群脂肪肝的发病情况及分布特征,探索脂肪肝发生发展的危险因素,为科学防控脂肪肝提供科学依据。方法 采用瞬时弹性成像技术方法诊断脂肪肝,检测指标包括体质指数、甘油三酯、总胆固醇、低密度脂蛋白胆固醇、高密度脂蛋白胆固醇。问卷调查含饮食习惯、运动、吸烟、饮酒、既往用药史等。结果 研究对象1443人,筛查出脂肪肝903人,脂肪肝总患病率为62.58%,其中男性患病率为73.16%、女性为39.69%。脂肪肝单因素分析:性别、年龄、体重指数、甘油三酯、总胆固醇、低密度蛋白胆固醇、饮食油腻类食物、吸烟、饮酒、降糖药、降脂药与脂肪肝有统计学意义(P<0.05),体重指数、甘油三酯的异常上升与脂肪肝的患病率有增加的趋势。脂肪肝多因素Logistic分析中:男性、年龄、体重指数升高、甘油三酯异常为脂肪肝的独立危险因数。结论 赤壁市体检人群中脂肪肝的患病率高,并随着年龄的增长增加的趋势;男性、年龄、肥胖、甘油三酯异常为脂肪肝的独立危险因数。在今后的脂肪肝防控工作中,加强健康教育和健康促进活动,提高居民健康意识,定期体检,做到早发现、早诊断、个性化治疗。

关键词: 脂肪肝;体检人群;危险因素

Abstract

Objective To understand the incidence and distribution characteristics of fatty liver among the physical examination population in Chibi City, explore the risk factors for the occurrence and development of fatty liver, and provide scientific basis for scientific prevention and control of fatty liver.
Methods Master the incidence and distribution characteristics of fatty liver among the physical examination population in Chibi City, explore the risk factors for the occurrence and development of fatty liver, and provide scientific basis for scientific prevention and control of fatty liver. Diagnosis of fatty liver using instantaneous elastic imaging technology, with detection indicators including body mass index, triglycerides, total cholesterol, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol. The questionnaire survey includes dietary habits, exercise, smoking, alcohol consumption, and past medication history.
Results Among the 1443 study subjects, 903 were screened for fatty liver disease, with a total prevalence rate of 62.58%, including 73.16% for males and 39.69% for females. Single factor analysis of fatty liver: Gender, age, body mass index, triglycerides, total cholesterol, low-density protein cholesterol, greasy diet, smoking, alcohol consumption, hypoglycemic drugs, and lipid-lowering drugs were statistically significant (P<0.05) with fatty liver. The abnormal increase in body mass index and triglycerides showed an increasing trend in the incidence of fatty liver. In the multivariate logistic analysis of fatty liver, male, age, increased body mass index, and abnormal triglycerides were independent risk factors for fatty liver.
Conclusion  s The prevalence of fatty liver is high among the physical examination population in Chibi City, and it tends to increase with age; Male, age, obesity, and abnormal triglycerides are independent risk factors for fatty liver disease. In the future prevention and control of fatty liver disease, we will strengthen health education and promotion activities, enhance residents' health awareness, conduct regular physical examinations, and achieve early detection, diagnosis, and personalized treatment.

Key words: Fatty liver; Physical examination population; Risk factors

参考文献 References

[1] 王贵强,王福生,成军,任红,庄辉,孙剑,李兰娟,李杰,孟庆华,赵景民,段钟平,侯金林,贾继东,唐红,盛吉芳,彭劼,鲁凤民,谢青,魏来.慢性乙型肝炎防治指南(2015更新版)[J].胃肠病学,2016,21(04):219-240.

[2] 陈玲玲,吴梅梅,林伟国,郑伟兵,朱琪.瞬时弹性成像技术在肝纤维化及脂肪肝诊断中的作用[J].福建医药杂志, 2020,42(02):29-32.

[3] 刘玉兰.非酒精性脂肪肝的流行病学现状[J].胃肠病学,2003(06)361-363.

[4] 孔晓丽,王广宇,徐春军,等.男女两性脂肪肝患病率随年龄变化的特征性分析[J].胃肠病学和肝病学杂志,2014, 23(9):1061-1065. 

[5] 吴玉梅.上海市某疗养院体检人群体重指数与血脂水平及非酒精性脂肪肝关系的调查研究[J]. 中国现代医生,2017,55(30):121-123,130.

[6] 栗卫东,王锡艳.白碱滩区全民健康体检3842例脂肪肝与体重指数的相关性调查[J].中国保健营养,2017,27 (11): 139. 

[7] 刘容,刘旭东,黎宝珍,等.体重指数对评估非酒精性脂肪性肝病患者肝纤维化的意义[J].世界最新医学信息文摘(连续型电子期刊),2020,20(53):128-130,136. 

[8] 丁芳,秦雨萌,曹群英,等.咸宁市健康体检人群非酒精性脂肪肝病的分布特征及危险因素分析[J]. 护理研究, 2017, 31(4):490-492. 

[9] 陈开,谢庆堂,郑荣阳,等.体检人群非酒精性脂肪肝危险因素病例对照研究[J].中国现代医生,2013,51(18): 13-14, 17.

[10] 王燕,马燕,吴琦琦,等.非酒精性脂肪性肝病进展性肝纤维化危险因素分析[J].胃肠病学和肝病学杂志,2019,28 (1): 96-100. 

[11] 李日娜,唐毅,高洋,等.联合弹性成像评估儿童肝纤维化[J].中国医学影像技术,2022,38(10):1519-1524.

[12] 王静,贺中云.中学生脂肪肝患病危险因素分析及健康干预[J].护理研究,2013,27(26):2906-2908.

[13] 于洋, 朱琳,胡敏.近五年非酒精性脂肪肝运动疗法的研究进展[J].军事体育学报, 2016, 35(04): 101-104.

[14] 王彦人,罗毅,张玫媚,等.杭州市某体检中心脂肪肝现状调查及危险因素分析[J].赣南医学院学报,2018,38(12): 1222-1227.

[15] 田峰,贾淑兰,丁华新,等.二甲双胍对新诊断2型糖尿病伴非酒精性脂肪肝的疗效观察[J].中国现代医生,2008, 46(15):19-20.

引用本文

潘石翠, 唐莉, 陈美惠, 高彬, 赤壁市体检人群脂肪肝的诊断及其危险因素分析[J]. 国际临床研究杂志, 2023; 7: (8) : 22-26.