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Open Access Article

International Journal of Clinical Research. 2023; 7: (5) ; 95-98 ; DOI: 10.12208/j.ijcr.20230228.

Effect of trimetazidine combined with atorvastatin calcium in the treatment of coronary heart disease
曲美他嗪联合阿托伐他汀钙治疗冠心病的效果

作者: 许丽丽 *

山东省淄博市临淄区皇城中心卫生院 山东淄博

*通讯作者: 许丽丽,单位:山东省淄博市临淄区皇城中心卫生院 山东淄博;

发布时间: 2023-05-23 总浏览量: 252

摘要

目的 讨论曲美他嗪与阿托伐他汀联合治疗冠心病的临床价值。方法 2020年3月至2021年5月期间,本次调查共纳入了68例冠心病患者,采取计算机表法的方式将其划分成两组,每组34例,当中对照组接受阿托伐他汀疗法,另一组则采取曲美他嗪结合阿托伐他汀钙疗法,以评估两组的治疗疗效。结果 经过诊断,我们观察到,在该项调查中,患者的左室射血分数显著增加,而且其左室收缩和舒张的末端比对照组小。患者的血脂水平也显著降低,而且其临床有效性也显著提升。患者的心电图有效性也显著提升,而且其心血管疾病的发病率也显著降低,差异呈现P<0.05。结论 曲美他嗪与阿托伐他汀联合治疗冠心病的效果确切,可改善患者的心功能指标,优化血脂指标,值得临床推广应用。

关键词: 冠心病;曲美他嗪;阿托伐他汀;心功能

Abstract

Objective: To discuss the clinical value of trimetazidine combined with atorvastatin in the treatment of coronary heart disease.
Methods: From March 2020 to May 2021, a total of 68 patients with coronary heart disease were enrolled in this study and divided into two groups with 34 patients in each group by computer table method. The control group received atorvastatin therapy and the other group received trimetazidine combined with atorvastatin calcium therapy to evaluate the therapeutic efficacy of the two groups.
Results: After diagnosis, we observed a significant increase in left ventricular ejection fraction in this study and a smaller left ventricular systolic and diastolic end than in the control group. Patients also had significantly lower blood lipid levels, and its clinical effectiveness was significantly improved. The ECG effectiveness of patients was also significantly improved, and the incidence of cardiovascular disease was also significantly reduced, the difference was P<0.05.
Conclusion  : The combination of trimetazidine and atorvastatin in the treatment of coronary heart disease is effective, can improve cardiac function indicators and optimize blood lipid indicators in patients with coronary heart disease, and is worthy of clinical promotion and application.

Key words: Coronary heart disease; Trimetazidine; Atorvastatin; Cardiac function

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引用本文

许丽丽, 曲美他嗪联合阿托伐他汀钙治疗冠心病的效果[J]. 国际临床研究杂志, 2023; 7: (5) : 95-98.