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Open Access Article

International Journal of Clinical Research. 2023; 7: (3) ; 159-161 ; DOI: 10.12208/j.ijcr.20230148.

Clinical efficacy of omeprazole and snake venom hemocoagulase in the treatment of upper gastrointestinal bleeding
奥美拉唑与蛇毒血凝酶治疗上消化道出血的临床疗效

作者: 王磊 *

密山市人民医院 黑龙江密山

*通讯作者: 王磊,单位:密山市人民医院 黑龙江密山;

发布时间: 2023-03-26 总浏览量: 417

摘要

目的 探究分析奥美拉唑治疗上消化道出血的临床效果。方法 选取于2021年1月至2022年12月,我院收治的上消化道出血患者共102例,作为本次研究对象。根据患者的入院序列数为基础,采用随机数字分组的方式,将102例患者随机分为对照组以及观察组。对照组采用法莫替丁进行治疗;观察组采用奥美拉唑结合白眉蛇毒血凝酶进行治疗。对比分析对照组以及观察组的临床症状消失时间;胃液PH值;胃肠激素指标、并发症发生率、治疗有效率、复发率。结果 观察组优于对照组,P<0.05。结论 对上消化道出血患者采用奥美拉唑结合白眉蛇毒血凝酶进行治疗,能够显著改善患者的临床症状消失时间;胃液PH值;胃肠激素指标、并发症发生率、治疗有效率、复发率;值得推广与应用。

关键词: 奥美拉唑;上消化道出血;临床症状消失时间;胃液PH值;胃肠激素指标;白眉蛇毒血凝酶

Abstract

Objective To investigate and analyze the clinical effect of omeprazole in the treatment of upper gastrointestinal bleeding.
Methods: A total of 102 patients with upper gastrointestinal bleeding admitted to our hospital from January 2021 to December 2022 were selected as the subjects of this study. Based on the number of admission sequences of patients, 102 patients were randomly divided into control group and observation group by random numerical grouping. The control group was treated with famotidine; The observation group was treated with omeprazole combined with white-browed snake venom hemocoagulin. The disappearance time of clinical symptoms in the control group and the observation group was compared and analyzed. pH of gastric juice; Gastrointestinal hormonal indicators, complication rate, treatment response rate, recurrence rate.
Results: The observation group was better than the control group, P<0.05.
Conclusion  : The treatment of omeprazole combined with white-browed snake venom hemagglutinin in patients with upper gastrointestinal bleeding can significantly improve the disappearance time of clinical symptoms. pH of gastric juice; gastrointestinal hormone indexes, complication rate, treatment response rate, recurrence rate; It is worth promoting and applying.

Key words: Omeprazole; Upper gastrointestinal bleeding; Time to disappearance of clinical symptoms; pH of gastric juice; Gastrointestinal hormonal indicators; White-browed snake venom hemocoagulase

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引用本文

王磊, 奥美拉唑与蛇毒血凝酶治疗上消化道出血的临床疗效[J]. 国际临床研究杂志, 2023; 7: (3) : 159-161.