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当前位置：国际临床研究杂志 > 2023年 7卷 (3)期

Open Access Article

International Journal of Clinical Research. 2023; 7: (3) ; 34-38 ; DOI: 10.12208/j.ijcr.20230114.

Current situation and research progress of maintenance therapy for recurrent or metastasis nasopharyngeal carcinoma
复发或转移性鼻咽癌维持治疗药物应用的现状及研究进展

作者： 张艳贤 *, 陆颖, 杨慧

中国广西壮族自治区柳州市工人医院肿瘤科广西柳州

*通讯作者：张艳贤,单位：中国广西壮族自治区柳州市工人医院肿瘤科广西柳州；

发布时间: 2023-03-23 总浏览量: 444

PDF 全文下载引用本文万方数据（WANFANG DATA）

摘要

鼻咽癌是我国高发恶性肿瘤之一，鼻咽癌经放化疗后能取得较好的肿瘤控制率，但仍有约20%的患者面临复发或转移。虽然辅助化疗可能进一步降低复发和死亡风险，但其在鼻咽癌中的疗效仍存在争议。因为大部分患者经历了放化疗后身体耐受性变差，无法完成这类高强度传统化疗。因此，寻找低毒有效、耐受性好的辅助治疗策略是目前临床上迫切需要解决的一大难题。近年来众多学者开始对转移性鼻咽癌维持治疗方案进行探索研究。目前在维持药物的选择、维持治疗的时长等问题上，还存在一定争议。全文对复发或转移性鼻咽癌的维持治疗现状及目前最新进展进行综述。

关键词： 鼻咽癌；维持治疗；进展

Abstract

Nasopharyngeal carcinoma (NPC) is one of the most common malignant tumors in China. NPC can achieve a good tumor control rate after radiotherapy and chemotherapy, but about 20% of the patients still face recurrence or metastasis. Although adjuvant chemotherapy may further reduce the risk of recurrence and death, the efficacy of adjuvant chemotherapy in NPC is still controversial. Because most patients experience poor physical tolerance after radiotherapy and chemotherapy, they are unable to complete this kind of high-intensity traditional chemotherapy. Therefore, finding an effective and tolerant adjuvant therapy strategy is an urgent problem to be solved in clinic at present. In recent years, many scholars began to explore the maintenance treatment of metastatic NPC. At present, there are still some disputes on the choice of drugs and the length of treatment. In this paper, the current situation and latest progress of maintenance and treatment of recurrent or metastatic NPC were reviewed.

Key words： Nasopharyngeal Carcinoma; Maintenance Therapy; Progress

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引用本文

张艳贤, 陆颖, 杨慧, 复发或转移性鼻咽癌维持治疗药物应用的现状及研究进展[J]. 国际临床研究杂志, 2023; 7: (3) : 34-38.

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