Analysis of anesthesia effect of dexmedetomidine in painless gastroscope
右美托咪定在无痛胃镜中的麻醉治疗效果分析

摘要

目的 分析右美托咪定在无痛胃镜中的麻醉治疗效果。方法 研究时间选取2020年10月-2021年10月，研究对象为我院接受无痛胃镜的患者86例，按照数字表随机交替排序法分为两组各43例，即采取丙泊酚麻醉的对照组与联合右美托咪定麻醉的观察组，比较两组的麻醉效果。结果 观察组的麻醉起效时间、持续时间优于对照组（t=8.154、13.165，P＜0.05），但苏醒恢复时间无差异（t=1.017，P＞0.05）；观察组在治疗时与治疗后的疼痛VAS评分低于对照组，镇静Ramsay评分高于对照组（t=6.716、5.424，t=5.190、7.702，P＜0.05）；观察组的不良反应发生率6.98%（3/43）低于对照组18.60%（8/43）（χ2=6.053，P＜0.05）。结论 在无痛胃镜中应用右美托咪定的麻醉效果良好，可显著提高镇痛镇静作用，且用药安全性更高，值得推广。

Abstract

Objective: To analyze the anesthetic effect of dexmedetomidine in painless gastroscopy.
Methods: From October 2020 to October 2021, 86 patients who received painless gastroscopy in our hospital were selected for the study. They were randomly divided into two groups, 43 patients in each group, according to the number table and the alternating order method. That is, the control group with propofol anesthesia and the observation group with dexmedetomidine anesthesia were used to compare the anesthetic effects of the two groups.
Results: The onset time and duration of anesthesia in the observation group were better than those in the control group (t=8.154, 13.165, P<0.05), but there was no difference in recovery time (t=1.017, P>0.05); The VAS score of pain during and after treatment in the observation group was lower than that in the control group, and the Ramsay score of sedation was higher than that in the control group (t=6.716, 5.424, t=5.190, 7.702, P<0.05); The incidence of adverse reactions in the observation group was 6.98% (3/43) lower than that in the control group (18.60% (8/43))(χ2=6.053，P＜0.05).
Conclusion  : The application of dexmedetomidine in painless gastroscope has a good anesthetic effect, can significantly improve the analgesic and sedative effects, and has higher drug safety, which is worthy of promotion.