摘要
目的 分析2021年冬至2022年春，某场区流感患儿发病24-48小时内血象变化，总结其变化规律，对不能行病原学检测诊断流感的基层医院提供可供参考的诊断依据，以便尽早用药治疗，避免延误病情。方法 对2021年12月至2022年4月集中出现的的一组以发热，头痛，四肢肌肉酸痛，乏力为典型症状的患儿血象进行统计分析，主要为发病24-48小时内的血象。统计病例数150例。统计其发病24-48小时内血常规白细胞计数，中性粒细胞百分、淋巴细胞百分比、C反应蛋白水平，最后进行整合和分析。结果 白细胞计数2.7~ 4.0×109/L患儿23例（15.3%），4.0~10.0×109/L患儿127例（84.7%）；中性粒细胞比率75%以上患儿106例（70.6%），68%~75%患儿44例（29.4%），为4~6岁前的前，包括4~6岁的患儿，68%以下患儿0例（0%）；淋巴细胞百分比在0~20%患儿148例（98.7%），20%~50%患儿2例（1.3%），50%以上患儿0例（0%）。患儿的C-反应蛋白水平为52.12±22.54（mg/L），而正常儿童C-反应蛋白水平2.14±1.05（mg/L）。结论 统计病例血象总趋势为白细胞计数正常或降低，中性粒细胞百分比明显升高，淋巴细胞百分比明显降低，C反应蛋白水平显著升高，这对不能进行病原学检测的基层单位诊断流感有较大的参考价值。
关键词： 儿童流感24-48h内血象；中性粒细胞升高；淋巴细胞抑制；基层流感诊断
Abstract
Objective: To analyze the blood changes in influenza children in some area within 24-48 hours in the spring of 2022, summarize their change rules, and provide reference diagnosis basis for basic hospitals that cannot conduct pathogen detection and diagnosis of influenza, so as to use medication as soon as possible and avoid delay in the disease. Methods: The analysis of children from December 2021 to April 2022 was mainly within 24-48 hours. The number of statistical cases was 150. Routine blood leukocyte count, neutrophil percentage and lymphocytes within 24-48 hours of onset were counted, and finally integrated and analyzed. Results: 23 children with 2.7~ 4.0 109 (15.3%) / L BC count, 4.0~10.0109 / L: 127 children (84.7%); Neutrophil ratio above 75% in 106 children (70.6%), 68%~75% Children 44 (29.4%), For the former years before age 4 to 6, Including children aged 4 to 6 years, There were 0 children below 68% (0%); Lymphocyte percentage in 0~20% of children in 148 patients (98.7%), Two children (1.3%) of 20%~50% children, More than 50% of the children had 0 cases (0%). The pediatric C-reactive protein level was 52.12 ± 22.54 (mg/L), while the normal pediatric C-reactive protein level was 2.14 ± 1.05 (mg/L). Conclusion : The general trend of statistical cases was normal or decreased leukocyte count, neutrophil percentage significantly increased, lymphocyte percentage significantly decreased, and C reactive protein level significantly increased, which has great reference value for the diagnosis of basic units for influenza.
Key words： Blood image within 24-48h of childhood influenza; Elevated neutrophils; Lymphocyte suppression; Basic diagnosis of influenza
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