Open Access Article
International Journal of Clinical Research. 2022; 6: (10) ; 82-84 ; DOI: 10.12208/j.ijcr.20220480.
Study on the relationship between restenosis after PCI and uric acid and adiponectin
PCI术后再狭窄与尿酸及脂联素的关联性研究
作者：
谷祥任,
钱滢,
刘俊林 *
长沙医学院 湖南长沙
*通讯作者：
刘俊林,单位：长沙医学院 湖南长沙；
发布时间: 2022-12-29 总浏览量: 249
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万方数据（WANFANG DATA）
摘要
经皮冠状动脉介入治疗（percutaneous coronary intervention，PCI）是治疗冠心病的重要手段之一。然而，随PCI手术的蓬勃开展，PCI术后并发症及复发再狭窄也越来越多，但其复发危险因素尚未明确。本研究主要研究评价了尿酸水平及脂联素水平对冠心病患者PCI术后复发的关联性。研究筛选了81名冠心病患者，对其PCI术前及术后12个月后尿酸水平及脂联素水平进行测定，分析尿酸与脂联素水平与PCI患者复发再狭窄的关联性。结果表明，高尿酸和低脂联素水平可明显增加PCI患者术后复发风险。高尿酸合并低脂联素可使PCI术后风险增加2.46倍，两者联合可作为PCI术后复发的可靠标志物。
关键词： 经皮冠状动脉介入治疗；尿酸；脂联素；复发
Abstract
Percutaneous coronary intervention (PCI) is one of the important means to treat coronary heart disease. However, with the vigorous development of PCI surgery, there are more and more complications and recurrent restenosis after PCI, but the risk factors of recurrence have not been clarified. The purpose of this study was to evaluate the correlation between the level of uric acid and adiponectin in patients with coronary heart disease after PCI. In this study, 81 patients with coronary heart disease were screened, and the levels of uric acid and adiponectin were measured before and 12 months after PCI to analyze the correlation between the levels of uric acid and adiponectin and the recurrence and restenosis of PCI patients. The results showed that high uric acid and low adiponectin levels could significantly increase the risk of recurrence after PCI. High uric acid combined with low adiponectin can increase the risk after PCI by 2.46 times, and the combination of the two can be used as a reliable marker of recurrence after PCI.
Key words： Percutaneous coronary intervention; uric acid; adiponectin; recurrence
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引用本文
谷祥任, 钱滢, 刘俊林, PCI术后再狭窄与尿酸及脂联素的关联性研究[J]. 国际临床研究杂志, 2022; 6: (10) : 82-84.