Effect of acarbose on blood glucose index in treating diabetes in community
阿卡波糖治疗社区糖尿病对血糖指标的影响

摘要

目的 分析社区糖尿病者中阿卡波糖治疗的干预效果。方法 选择近2年（2020年1月-2022年2月）于社区诊治的糖尿病者280例，回顾临床资料，将加入阿卡波糖治疗的140例作为观察组，采用常规治疗的140例患者作为对照组，对比两组临床疗效。结果 治疗后，观察组患者空腹血糖（6.28±2.11）mmol/L，餐后2h血糖（8.04±2.38）mmol/L，糖化血红蛋白（6.42±0.62）mmol/L。对照组患者空腹血糖（8.89±2.28）mmol/L，餐后2h血糖（10.86±3.24）mmol/L，糖化血红蛋白（8.89±0.95）mmol/L。组间对比差异有统计学意义（P<0.05）；观察组治疗总有效率93.57%，对照组治疗总有效率88.57%。组间对比差异有统计学意义（P<0.05）；随访中发现，观察组不良反应率5.71%，对照组不良反应率2.86%。组间对比差异无统计学意义（P>0.05）。结论 在社区糖尿病患者中加入阿卡波糖治疗，可在很大程度上控制血糖水平，提高治疗效果，有助于提高其生活质量，临床应用价值确切。

Abstract

Objective To analyze the intervention effect of acarbose treatment on diabetes in community.
Methods: 280 patients with diabetes diagnosed and treated in the community in the past two years (January 2020 February 2022) were selected. The clinical data were reviewed. 140 patients who were treated with acarbose were selected as the observation group and 140 patients who were treated with conventional therapy were selected as the control group. The clinical effects of the two groups were compared.
Results: After treatment, the fasting blood glucose (6.28 ± 2.11) mmol/L, blood glucose (8.04 ± 2.38) mmol/L, and glycosylated hemoglobin (6.42 ± 0.62) mmol/L in the observation group. In the control group, fasting blood glucose (8.89 ± 2.28) mmol/L, blood glucose (10.86 ± 3.24) mmol/L, and glycosylated hemoglobin (8.89 ± 0.95) mmol/L at 2h after meal were observed. The difference between groups was statistically significant (P<0.05); The total effective rate was 93.57% in the observation group and 88.57% in the control group. The difference between groups was statistically significant (P<0.05); During follow-up, it was found that the adverse reaction rate of the observation group was 5.71%, and that of the control group was 2.86%. There was no significant difference between groups (P>0.05).
Conclusion  : adding acarbose to diabetes patients in the community can control the blood sugar level to a great extent, improve the treatment effect, help to improve their quality of life, and have definite clinical application value.