Observation on the effect of Badu Shengji Powder combined with MEBO gauze on dressing change after anorectal surgery
拔毒生肌散联合湿润烧伤膏纱条用于肛肠疾病术后换药的疗效观察

摘要

目的：探索拔毒生肌散联合湿润烧伤膏纱条用于肛肠疾病术后换药的临床疗效，为患者术后伤口恢复提供保障。方法 共纳入肛瘘、肛周脓肿术后患者70例，随机分为实验组和对照组，各35例。对照组采用康复新液清洁创面，加之牛黄痔清栓纳肛及藻酸盐敷料填塞创面，实验组在对照组换药基础上采用拔毒生肌散联合湿润烧伤膏纱条进行换药操作，观察两组患者创面肉芽生长情况、脓性分泌物及伤口疼痛情况，监测用药安全。结果 2组术后3d创面肉芽生长情况及分泌物评分比较，差异无统计学意义（P>0.05）,实验组术后7d、14d创面肉芽生长情况评分（2.37±0.49、1.37±0.65）及分泌物评分（1.89±0.47、1.26±0.56）显著低于对照组（2.63±0.49、1.74±0.51；2.17±0.51、1.30±0.55），差异具有统计学意义（P<0.05）。实验组术后3d、7d、14d术后伤口疼痛评分（7.20±0.80、6.34±0.59、4.11±0.90）显著低于对照组（7.51±0.56、6.66±0.54、5.17±0.75），差异具有统计学意义（P<0.05）。结论 拔毒生肌散联合湿润烧伤膏纱条用于肛肠疾病术后创面换药安全有效，值得在临床中推广使用。

Abstract

Objective To explore the clinical efficacy of Budu Shengji powder combined with MEBO gauze in dressing change after anorectal diseases, and to provide guarantee for the postoperative wound recovery of patients.
Methods A total of 70 patients with anal fistula and perianal abscess after surgery were enrolled and randomly divided into experimental group and control group, 35 cases in each group. Control group adopts the new recovery liquid cleaning wounds, combined with the anus hemorrhoids and Niuhuang Zhiqing suppository and alginate dressings stuffing, the experimental group in the control group treatment on the basis of using poison born muscle pull loose joint article moist burn cream yarn for switching operation, observe two groups of patients with wound granulation growth situation, purulent secretion and wound pain, monitoring of drug safety.
Results There was no significant difference in wound granulation growth and secretion score between the two groups at 3 days after operation (P>0.05). The scores of granulation growth and secretion at 7 and 14 days after operation in the experimental group (2.37±0.49, 1.37±0.65) and 1.89±0.47, 1.26±0.56) were significantly lower than those in the control group (2.63±0.49, 1.74±0.51; 2.17±0.51, 1.30±0.55), and the difference was statistically significant (P<0.05). The wound pain scores of the experimental group (7.20±0.80, 6.34±0.59, 4.11±0.90) were significantly lower than those of the control group (7.51±0.56, 6.66±0.54, 5.17±0.75) at 3 days, 7 days, and 14 days after operation, and the differences were statistically significant (P<0.05).
Conclusion   Budu Shengji powder combined with MEBO gauze is safe and effective for wound dressing change after anorectal diseases, which is worthy of clinical application.