摘要
目的 研究覆膜支架治疗食管癌食管狭窄及食管-支气管瘘效果。方法 选择2017年03月-2021年12月到本院治疗食管癌食管狭窄及食管-支气管瘘患者共116例作为观察对象，随机分为实验和对照两组，分析两组疗效。结果 实验组治疗效果57/58（98.28％）优于对照组治疗效果50/58（86.21％），P＜0.05；治疗后，两组临床指标（吞咽功能、吻合口狭窄部位直径）对比，实验组各项指标均优于对照组，P＜0.05，实验组生存质量评分高于对照组，P＜0.05；实验组并发症出现率1/58（1.72％）低于对照组8/58（13.79％），P＜0.05。结论 运用覆膜支架治疗食管癌食管狭窄及食管-支气管瘘疗效显著，安全性高，值得运用。
关键词： 覆膜支架；食管癌食管狭窄；食管-支气管瘘；疗效；并发症
Abstract
Objective: To study the effect of covered stent in the treatment of esophageal cancer, esophageal stenosis and esophageal bronchial fistula. Methods: a total of 116 patients with esophageal cancer, esophageal stenosis and esophageal bronchial fistula treated in our hospital from December 2021 to July 2022 were randomly divided into experimental and control groups to analyze the efficacy of the two groups. Results: the therapeutic effect of the experimental group was 57 / 58 (98.28%) better than that of the control group (50 / 58 (86.21%), P < 0.05; After treatment, the clinical indexes (swallowing function and diameter of anastomotic stenosis) of the two groups were compared. All indexes of the experimental group were better than those of the control group (P < 0.05). The quality of life score of the experimental group was higher than that of the control group (P < 0.05); The complication rate of the experimental group was 1 / 58 (1.72%) lower than that of the control group (8 / 58 (13.79%) (P < 0.05). Conclusion : the covered stent is effective and safe in the treatment of esophageal cancer, esophageal stenosis and esophageal bronchial fistula.
Key words： Covered Stent; Esophageal Cancer And Esophageal Stenosis; Esophageal Bronchial Fistula; Curative Effect; Complication
参考文献 References
[1] 黄妹,韩明,文剑波. 内放射支架与普通覆膜支架治疗中晚期食管癌疗效及并发症比较的Meta分析:943例[J]. 世界华人消化杂志,2020,28(15):699-709.
[2] 徐文静,江宁,张倩,等. 124例食管癌伴食管瘘患者的预后分析及营养支持模式探讨[J]. 临床肿瘤学杂志,2020, 25 (11): 999-1004.
[3] 宋群容,张涛,梁红亮. DZAS-Ⅰ型覆膜支架置入术治疗难治性食管癌术后吻合口狭窄的临床效果分析[J]. 中国医学前沿杂志（电子版）,2020,12(7):115-118.
[4] 梁丽君,康艳丽. 内镜下放置覆膜食管支架治疗晚期食管癌癌性梗阻成功植入率的分析[J]. 实用癌症杂志,2020,35(1):172-174.
[5] 曾德辉,曾安祥,王胜炳. 内镜下覆膜食管支架治疗食管癌性狭窄及食管气管(纵膈)瘘的临床应用价值[J]. 中国医药科学,2020,10(7):287-290.
[6] 王亚丽,马新宇,崔艳艳,等. 放射性125I粒子覆膜支架植入对蒙古族中晚期食管癌的有效性和安全性分析的研究[J]. 世界最新医学信息文摘（连续型电子期刊）,2020,20(46):44,49.
[7] 戴守方,李顺宗,王瑞锋,等. 中晚期食管癌覆膜支架与粒子支架并发症的比较[J]. 世界最新医学信息文摘（连续型电子期刊）,2020,20(33):43-44.
[8] 王志化,程兆明,曹亮,等. 覆膜自膨式食管金属支架治疗食管恶性狭窄的疗效研究[J]. 中国医药科学,2020, 10(22): 190-192,203
[9] 张力苹,张启周,栗国梁,等. DSA引导下125I粒子覆膜食道支架联合TP方案化疗治疗晚期食管癌[J]. 牡丹江医学院学报,2020,41(1):98-101,108.
[10] 江南,赵一,朱陆云,等. 比较放射性支架与覆膜自膨式金属支架在中晚期食管癌患者中的临床疗效[J]. 世界最新医学信息文摘（连续型电子期刊）,2020,20(27): 181-182.