摘要
目的 针对我院住院的癌痛患者的治疗状况进行调查分析,芜湖市某三甲医院癌痛患者阿片类药物使用的知信行状况,探讨合理用药方法。方法 实验时间段设置在2021年1月到2022年6月,在该时段内检索芜湖市某三甲医院癌痛住院150例患者的电子病历,针对阿片类药物的用药频度、药物利用指数进行记录,同时针对所有患者进行知信行调查,分析患者对于阿片类药物使用规范性、合理性的了解度。结果 在研究结果中显示,用药频度最高的药物为曲马多缓释片,其次为芬太尼透皮贴片和羟考酮控释片。而药物利用指数最高的阿片类药物为芬太尼透皮贴片。在针对150例患者进行知信行相关内容的调查时发现患者对于药物的使用规范性和合理性,整体来说了解度较差,大部分患者并不了解这类药物在应用时存在明显的不规范情况,合格率仅为65(43.33%)。结论 在针对癌痛患者进行临床镇痛处理时,研究人员需要关注患者的个体状况,并给予患者有效的用药指导和合理用药,尽可能保障患者在接受治疗期间的用药规范性,降低患者在用药期间出现的不良反应,使患者的治疗总有效率和镇痛效果得到提升。
关键词: 癌痛患者;阿片类药物;用药管理;研究分析
Abstract
Objective: To investigate and analyze the treatment status of cancer pain patients hospitalized in our hospital, the knowledge, belief and practice status of opioid use in cancer pain patients in a tertiary a hospital in Wuhu, and to explore rational drug use methods. Methods: the experimental period was set from September 2017 to April 2022. During this period, the electronic medical records of 150 patients with cancer pain hospitalized in a tertiary a hospital in Wuhu were retrieved, and the frequency of opioid use and drug utilization index were recorded. At the same time, a knowledge and practice survey was conducted for all patients to analyze the patients' understanding of the standardization and rationality of opioid use. Results: the results showed that tramadol sustained-release tablets were the most frequently used drugs, followed by fentanyl transdermal patches and oxycodone controlled-release tablets. The opioid with the highest drug utilization index is fentanyl transdermal patch. In the investigation of knowledge, belief and practice related content for 150 patients, it was found that patients' understanding of the standardization and rationality of drug use was poor on the whole. Most patients did not understand that there were obvious irregularities in the application of this kind of drugs, and the qualified rate was only 489 (40.75%). Conclusion : when carrying out clinical analgesic treatment for cancer pain patients, researchers need to pay attention to the individual situation of patients, give effective medication guidance and rational medication to patients, try to ensure the standardization of medication during treatment, reduce the adverse reactions of patients during medication, and improve the total treatment efficiency and analgesic effect of patients.
Key words: Cancer Pain Patients; Opioids; Medication Management; Research Analysis
参考文献 References
[1] 魏春英,连丽钦,刘慧,陈娥,罗爱华,郑晓玲,吴金通,薛水兰. 使用阿片类药物管控对患者自我管理水平的影响研究[J]. 中国医药指南,2022,20(19):7-10.
[2] 杜莉,许远,张炼,徐桂花,王桂芬,刘震杰. 自拟癌痛止痛贴膏联合盐酸羟考酮治疗难治性癌性疼痛的效果观察[J]. 中华全科医学,2022,20(07):1094-1097+1121.
[3] 宋洪丽,冯永利,王耀焓,冯利. 益肾祛痛颗粒对骨癌痛大鼠痛觉敏化及骨破坏的影响[J]. 海南医学院学报:1-14.
[4] 凌颖娴,胡聪俐,何瑛,吴雪丹,冯智英,饶跃峰. 阿片类药物治疗儿童癌痛的研究进展[J]. 中国现代应用药学,2022,39(12):1532-1538.
[5] 李慧,高利利. 认知和行为护理干预对肿瘤患者口服阿片类药物依从性的临床研究[J]. 贵州医药,2022, 46(06): 985-986.
[6] 刘杰,王萌萌,杨佃会,崔鑫鑫. 疏肝调神针法对偏头痛大鼠脑组织阿片类受体表达及血清炎性因子水平的影响[J]. 针刺研究,2022,47(06):510-516.
[7] 张进,肖正权,聂菁,饶竟,李文均. 肿瘤重症患者发生亚谵妄综合征影响因素及护理方案的构建及应用[J]. 实用医学杂志,2022,38(12):1548-1552.
[8] 刘树山,劳正胤,黄松松,程东群. 癌理通膏外敷配合强阿片类止痛药对癌性骨痛的临床疗效观察[J]. 中国肿瘤临床与康复,2022,29(06):717-720.