Application of biochemical test in the diagnosis of diabetes mellitus
生化检验在糖尿病诊断中的应用

摘要

目的 探讨生化检验在糖尿病诊断中的应用价值。方法 选择2020年4月至2021年4月我院收治的60例糖尿病患者作为实验组，再选择同时间段的60例健康体检者作为对照组。通常在早上6到8时取血，受检者检验前12h禁食、禁水，不服用降糖药物，避免运动。观察两组糖耐受试验值、空腹血糖水平、胰岛素含量、C肽水平和血脂指标，包括高密度脂蛋白-胆固醇（HDL-C）、低密度脂蛋白-胆固醇（LDL-C）、高脂血症（TG）、总胆固醇(TC)含量。结果 实验组糖耐受试验值（14.16±2.75）mmol/L、空腹血糖（7.64±1.73）mmol/L均明显高于对照组糖耐受试验值（8.04±1.12）mmol/L、空腹血糖（4.62±0.86）mmol/L，胰岛素（104.63±73.25）pmol/L、C肽（2.11±0.97）nmol/L均显著高于对照组胰岛素（45.31±18.56）pmol/L、C肽（0.68±0.27）nmol/L，HDL-C（1.28±0.33）mmol/L、LDL-C（3.52±0.81）mmol/L、TG（3.27±0.89）mmol/L、TC（5.39±1.18）mmol/L均明显优于对照组HDL-C（1.57±0.48）mmol/L、LDL-C（2.57±0.53）mmol/L、TG（1.73±0.62）mmol/L、TC（4.23±0.85）mmol/L，差异有统计学意义（P<0.05）。结论 生化检验在糖尿病诊断中的应用价值较高，能准确测量糖耐受试验值、空腹血糖水平、胰岛素含量、C肽水平、血脂等各项指标，为判断糖尿病提供理论依据，有利于后续制定治疗方案，延缓病情发展，减少疾病不良影响，维持身体健康，提高患者的生活质量。

Abstract

Objective: To explore the application value of biochemical test in the diagnosis of diabetes mellitus.
Methods: 60 cases of diabetes patients admitted to our hospital from April 2020 to April 2021 were selected as the experimental group, and 60 cases of healthy physical examination in the same period were selected as the control group. Blood is usually taken from 6 to 8 in the morning, and subjects are forbidden from fasting and water, do not take hypoglycemic drugs, and avoid exercise 12 hours before examination. The glucose tolerance test value, fasting blood glucose level, insulin content, C-peptide level and blood lipid indexes, including high density lipoprotein-cholesterol (HDL-C), low density lipoprotein-cholesterol (LDL-C), hyperlipidemia (TG) and total cholesterol (TC) contents in both groups were observed.
Results: The glucose tolerance test values of the experimental group (14.16±2.75) mmol/L and fasting blood glucose (7.64±1.73) mmol/L were significantly higher than those of the control group (8.04±1.12) mmol/L and fasting blood glucose (4.62±0.86) mmol/L. Insulin (104.63±73.25) pmol/L and C-peptide (2.11±0.97) nmol/L were significantly higher than those in control group (45.31±18.56) pmol/L and C-peptide (0.68±0.27) nmol/L. Hdl-c (1.28±0.33) mmol/L, LDL-C (3.52±0.81) mmol/L, TG (3.27±0.89) mmol/L, TC (5.39±1.18) mmol/L were significantly better than control group HDL-C (1.57±0.48) mmol/L, LDL- C (2.57±0.53) mmol/L, TG (1.73±0.62) mmol/L, TC (4.23±0.85) mmol/L, the differences were statistically significant (P<0.05).
Conclusion  : biochemical examination in the diagnosis of diabetes value is higher, can accurately measure the glucose tolerance test value, fasting blood glucose, insulin, C peptide levels, blood fat, such as the indicators, as to provide theoretical basis for judgment of diabetes, is conducive to the follow-up treatment, delay the progression and reduce disease, maintain a healthy body, improve the quality of life of patients.